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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, plays at the Pediatric Hematology Oncology Clinic at the University of North Carolina Hospital during a monthly check-up on December 27, 2013.
    laruesjourney0126.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, is examined by Dr. Troutman at the Pediatric Hematology Oncology Clinic at the University of North Carolina Hospital on December 27, 2013, exactly one year after her diagnosis. Dr. Troutman is the doctor who took the phone call that resulted in Larue being transported to UNC.
    laruesjourney0129.JPG
  • Holly Larue Frizzelle, 2, and her mother Leilani Frizzelle sit in Larue's room at UNC Children's Hospital in December of 2012On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0033.jpg
  • Pictured is the view from Larue's room just before being discharged to leave. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0034.jpg
  • Holly Larue Frizzelle sleeps in her room at UNC Hospital in December 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0003.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by her pharmacist.
    laruesjourney0085.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by Tutu Divine of Southport, N.C.
    laruesjourney0081.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0105.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0018.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2 plays with some of the items commonly encountered during surgery in her room at UNC Hospital in December 2012. The hospital staff allow children to play with the items to make them more comfortable before they have surgery.
    laruesjourney0008.jpg
  • Leilani Frizzelle blows bubbles with her daughter Holly Larue, 2 in Larue's room in December 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0005.jpg
  • The calender marking off days until the first phase of treatment is complete is pictured on the refrigerator. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0079.jpg
  • Holly Larue Frizzelle, 2, swings at a birthday party in January 2013. The party was the first contact with children Larue had in more than a month due to her compromised immune system. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0068.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle and Holly Larue Frizzelle, 2, sleep in a hotel in Chapel Hill, N.C. before an early morning sedation appointment at the UNC Cancer Hospital.
    laruesjourney0061.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
    laruesjourney0052.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, walks on Wrightsville Beach with her mother Leilani Frizzelle during an unseasonably warm January day. Larue was in the Induction phase of treatment for Acute Lymphoblastic Leukemia and was only allowed minimum contact with others due to a compromised immune system. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
    laruesjourney0045.JPG
  • Holly Larue Frizzelle plays at her best friend's home during July 4th. This was the first time she was able to play with other children during the summer due to treatment.
    laruesjourney0108.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, and her Mother Leilani Frizzelle sit in her room after Leilani shaved her head for Childhood Cancer Awareness Month.
    laruesjourney0122.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, and her mother Leilani Frizzelle share a laugh after Leilani shaved her head for Childhood Cancer Awareness Month.
    laruesjourney0123.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0136.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0098.jpg
  • Holly Larue Frizzelle, 3 plays outsider her home in Wilmington, N.C. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0089.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle sits with her daughter Holly Larue Frizzelle, 2, as Larue receives a blood transfusion at The UNC Caner Hospital in Chapel Hill, N.C.
    laruesjourney0051.jpg
  • Holly Larue Frizzelle, 2, falls asleep in her bed in January 2013. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0048.jpg
  • Holly Larue Frizzelle, 2, eats a meal after a sedation appointment at the UNC Cancer Hospital in January 2013. For sedation appointments Larue is not allowed to eat after midnight before appointment. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0036.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0032.jpg
  • Leilani Frizzelle cleans her daughter Larue's baby doll at UNC Children's Hospital in December of 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0027.jpg
  • Leilani Frizzelle brushes her daughter, Holly Larue Frizzelle's hair in Larue's room at UNC Hospital in December 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0021.jpg
  • Ella Gardner, 5 and her Father Eric pose for a photo with Holly Larue Frizzelle, 2  and her mother Leilani at Ella's fifth birthday party. Ella chose to dedicate her fifth birthday party to Larue and accept donations in lieu of presents. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0069.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
    laruesjourney0065.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
    laruesjourney0067.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, plays with an ipad at her home in Wilmington, N.C. during the induction phase of her chemotherapy treatment. The steroids she took compromised her immune system and caused her to be isolated from other people.
    laruesjourney0058.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, plays with an ipad at her home in Wilmington, N.C. during the induction phase of her chemotherapy treatment. The steroids she took compromised her immune system and caused her to be isolated from other people.
    laruesjourney0057.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
    laruesjourney0056.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
    laruesjourney0055.JPG
  • Holly Larue Frizzelle plays at her best friend's home during July 4th. This was the first time she was able to play with other children during the summer due to treatment.
    laruesjourney0112.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle shaves her head as her daughter Holly Larue Frizzelle, 3, looks on.
    laruesjourney0125.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0133.JPG
  • Holly Larue Frizzelle swings in her brothers nursery. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0104.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0102.jpg
  • Pictured is the kit that contained everything we needed to administer chemotherapy at home. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0101.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, sleeps in her room at UNC Children's Hospital in December of 2012.
    laruesjourney0030.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, is pictured in her room at UNC Children's Hospital with her central line exposed.
    laruesjourney0024.jpg
  • Holly Larue Frizzelle, 2 plays with her mother Leilani in her room at UNC Hospital in December 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0016.jpg
  • A sibling meeting their younger sibling for the first time is one of the most important moments of a family's life. This collection of images captures the first two meetings of Larue, 3 and her brother Rory.
    laruesjourney0117.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by her pharmacist.
    laruesjourney0086.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by Tutu Divine of Southport, N.C.
    laruesjourney0080.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0075.JPG
  • Holly Larue Frizzelle visits the N.C. Aquarium for the first time since being diagnosed with Leukemia. Just a few days before being diagnosed we visited the aquarium and she was so weak she had to be pushed in a stroller.
    laruesjourney0078.JPG
  • Holly Larue Frizzelle visits the N.C. Aquarium for the first time since being diagnosed with Leukemia. Just a few days before being diagnosed we visited the aquarium and she was so weak she had to be pushed in a stroller.
    laruesjourney0077.JPG
  • Holly Larue Frizzelle plays on Wrightsville Beach in February 2013. This was the first time Larue visited the beach after completing the 'Induction' phase of chemotherapy.
    laruesjourney0072.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, has her central line accessed at the UNC Cancer Hospital in Chapel Hill, N.C. Her central line allows doctors and nurses to administer medicine intravenously.
    laruesjourney0063.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, plays with an ipad at her home in Wilmington, N.C. during the induction phase of her chemotherapy treatment. The steroids she took compromised her immune system and caused her to be isolated from other people.
    laruesjourney0059.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
    laruesjourney0047.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, walks on Wrightsville Beach with her mother Leilani Frizzelle during an unseasonably warm January day. Larue was in the Induction phase of treatment for Acute Lymphoblastic Leukemia and was only allowed minimum contact with others due to a compromised immune system. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
    laruesjourney0044.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0107.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, covers her ears at the sound of the clippers her mother Leilani Frizzelle uses to shave her head for Childhood Cancer Awareness Month.
    laruesjourney0124.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, opens Christmas presents.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0134.JPG
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0137.JPG
  • Holly Larue Frizzelle sits with her grandmother. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0114.jpg
  • Pictured is one of the many cards Larue received from supporters. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0093.jpg
  • Holly Larue Frizzelle lies on the couch of her family home in Wilmington, N.C. She was on a steroid for Leukemia that increased her appetite and made her very lethargic. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0092.jpg
  • Holly Larue Frizzelle plays with her mother Leilani Frizzelle in their backyard in Wilmington, N.C. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0091.jpg
  • Holly Larue Frizzelle swings in her backyard in Wilmington, N.C. During her chemotherapy she was restricted from playing with other children and spen much of her time playing alone in her backyard. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0090.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0037.jpg
  • Holly Larue Frizzelle, 2, and her mother Leilani Frizzelle sit in Larue's room at UNC Children's Hospital in December of 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0031.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, sleeps in her room at UNC Children's Hospital in December of 2012.
    laruesjourney0029.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, sleeps in her room at UNC Children's Hospital in December of 2012.
    laruesjourney0028.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2 is visited by her grandmother and grandfather in her room at UNC Hospital in December 2012.
    laruesjourney0015.jpg
  • Holly Larue Frizzelle has an ecocardiogram before beginning chemotherapy at UNC Hospital in December 2012. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0013.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle has a blood transfusion in her room at UNC Hospital in December 2012.
    laruesjourney0012.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2 plays with some of the items commonly encountered during surgery in her room at UNC Hospital in December 2012. The hospital staff allow children to play with the items to make them more comfortable before they have surgery.
    laruesjourney0010.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2 plays with some of the items commonly encountered during surgery in her room at UNC Hospital in December 2012. The hospital staff allow children to play with the items to make them more comfortable before they have surgery.
    laruesjourney0007.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0096.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0094.jpg
  • A sibling meeting their younger sibling for the first time is one of the most important moments of a family's life. This collection of images captures the first two meetings of Larue, 3 and her brother Rory.
    laruesjourney0118.jpg
  • A sibling meeting their younger sibling for the first time is one of the most important moments of a family's life. This collection of images captures the first two meetings of Larue, 3 and her brother Rory.
    laruesjourney0116.jpg
  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
    laruesjourney0087.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by her pharmacist.
    laruesjourney0084.jpg
  • Holly Larue Frizzelle, 2 poses for a portrait in a tutu that was donated to her by Tutu Divine of Southport, N.C.
    laruesjourney0082.jpg
  • Holly Larue Frizzelle visits the N.C. Aquarium for the first time since being diagnosed with Leukemia. Just a few days before being diagnosed we visited the aquarium and she was so weak she had to be pushed in a stroller.
    laruesjourney0076.JPG
  • Holly Larue Frizzelle plays on Wrightsville Beach in February 2013. This was the first time Larue visited the beach after completing the 'Induction' phase of chemotherapy.
    laruesjourney0074.JPG
  • Holly Larue Frizzelle plays on Wrightsville Beach in February 2013. This was the first time Larue visited the beach after completing the 'Induction' phase of chemotherapy.
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  • Holly Larue Frizzelle plays on Wrightsville Beach in February 2013. This was the first time Larue visited the beach after completing the 'Induction' phase of chemotherapy.
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  • Holly Larue Frizzelle plays alone at her home in Wilmingotn. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle cuts her daughter Holly Larue Frizzelle's hair at their home. Larue's hair had begun to thin during chemotherapy and Leilani cut to blend in until it fell out.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, walks on Wrightsville Beach with her mother Leilani Frizzelle during an unseasonably warm January day. Larue was in the Induction phase of treatment for Acute Lymphoblastic Leukemia and was only allowed minimum contact with others due to a compromised immune system. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 2, walks on Wrightsville Beach with her mother Leilani Frizzelle during an unseasonably warm January day. Larue was in the Induction phase of treatment for Acute Lymphoblastic Leukemia and was only allowed minimum contact with others due to a compromised immune system. Leilani Frizzelle and her daughter Holly Larue Frizzelle, 2, enjoy an unseasonably warm January evening at Wrightsville Beach during Larue's induction phase of treatment for leukemia. During this phase Larue's contact with others is limited due to a compromised immune system.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, sits up in her bed Christmas Morning 2013. The Christmas of 2012 she was so sick from Leukemia she needed help getting out of bed.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, plays with a pile of hair left after her mother shaved her head.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment. Holly Larue Frizzelle, 3, plays a game in a hotel room in Chapel Hill, N.C. During her treatment at UNC hospital she routinely stays in the hotel due to the early clinic appointments.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • Holly Larue Frizzelle sits on the couch in her living room as chemotherapy is administered thought a pump. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • Holly Larue Frizzelle, 3, turns away from the camera outside her home in Wilmington. During the phase known as Delayed Intensification Larue became agitated by having her photo taken. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • Holly Larue Frizzelle plays on a table with flowers sent to her by well wishers. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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  • Holly Larue Frizzelle, 2, sleeps in her bed for the first time in more than a week in January 2013. On December 27, 2012 two year old Holly Larue Frizzelle was diagnosed with Acute Lymphoblastic Leukemia. What began as a stomach ache and visit to her regular pediatrician led to a hospital admission, transport to the University of North Carolina Children's Hospital, and more than two years of treatment.
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